ACB Wakame Bioferment Advanced

Stop band-aiding the problem and find a solution! Skin loses its luminescence over time and begins to have a dry, dull appearance due to the amount of toxins we encounter every day. It is critical that we provide the skin with nutrients, moisture and a way to detoxify. ACB Wakame Bioferment Advanced can efficiently detoxify the skin by targeting internal pollution, where the problem starts. Developed from cultured wakame cells, ACB Wakame Bioferment Advanced is the solution to cellular longevity. This product targets the mitochondria, which has been shown to contribute to the longevity of cells and minimize damage at a cellular level. ACB Wakame Bioferment Advanced can promote longevity while also providing powerful antioxidant benefits to personal care and cosmetic formulations.

Efficacy Assays

  • 15 Minute Oxygen Consumption Assay

    Meaures changes in oxygen consumption by fibroblasts in 15 minutes... Read More

  • 15 Minute Oxygen Consumption Assay

    The results indicate that ACB Wakame Bioferment Advanced is capable of inducing changes in oxygen consumption to fibroblasts. Compared to the untreated control, ACB Wakame Bioferment increased oxygen consumption by 26.8%. These changes are comparable to the changes achieved using LYCD and ACB Yogurt Dermal Respiratory Factor.

  • 24 Hour Oxygen Consumption Assay

    Meaures changes in oxygen consumption by fibroblasts over 24 hours... Read More

  • 24 Hour Oxygen Consumption Assay

    The results demonstrate that ACB Wakame Bioferment Advanced is capable of increasing oxygen consumption by 31% compared to the untreated control.

  • ROS Formation

    Determines the inhibition of ROS formation by a test material... Read More

  • ROS Formation

    In this study, dermal fibroblasts were loaded with DCF and then treated with various test materials for 1 hour. At 0 and 1 hour intracellular fluorescence was measured to determine the amount of ROS formation associated with each test material. Over the course of the incubation, treatment with ascorbic acid was observed to significantly reduce ROS formation while treatment with H2O2 was observed to significantly increase ROS formation. Interestingly, treatment with ACB Wakame Bioferment Advanced was observed to reduce ROS formation compared to the untreated control.

  • ORAC Assay

    Measures a material's potential to protect against oxidative stress or ROS... Read More

  • ORAC Assay

    ACB Wakame Bioferment Advanced exhibited potent antioxidant activity comparable to 100M Trolox®. The antioxidant capacity of ACB Wakame Bioferment Advanced increased as the concentration increased, as a result we can assure that its ability to minimize oxidative stress is dose dependent.

  • NO Formation

    Measures the effect of NO synthesis by the test material... Read More

  • NO Formation

    In this study, dermal fibroblasts were loaded with DAF-2DA and then treated with various test materials for 6 hours. At 0, 1 and 6 hours intracellular fluorescence was measured to determine the amount of NO formation associated with each test material. Over the course of the incubation, treatment with ascorbic acid was observed to significantly reduce NO formation while treatment with H2O2 was observed to significantly increase NO formation. Interestingly, treatment with ACB Wakame Bioferment Advanced was observed to reduce NO formation when compared to the untreated control.

  • Procollagen Assay

    Stimulates procollagen production in situ... Read More

  • Procollagen Assay

    The ELISA indicates that ACB Wakame Bioferment Advanced is capable of increasing the expression of procollagen type 1-C peptide in the fibroblast cell culture model. ACB Wakame Bioferment Advanced was shown to be comparable to Magnesium Ascorbyl Phosphate in increasing the synthesis of Collagen Type 1. These findings suggest that ACB Wakame Bioferment Advanced is useful in cosmetic preparations to stimulate collagen type 1 production in situ.

  • Collagen Type I ELISA Assay

    Increases collagen I synthesis in in-vitro cultured dermal fibroblasts... Read More

  • Collagen Type I ELISA Assay

    The results indicate that ACB Wakame Bioferment Advanced is capable of increasing collagen I synthesis compared to both the positive and negative controls. Fibroblasts treated with ACB Wakame Bioferment Advanced increased collagen I synthesis by 58%, 108% and 168% respectively. As anticipated the rate of increase for collagen synthesis using ACB Wakame Bioferment Advanced appears to be dose dependent.

  • DNA MicroArray

    Measures changes in the expression of genes by the selected cell type... Read More

  • DNA MicroArray

    We used a DNA microarray to create a comprehensive picture of how fibroblasts respond to ACB Wakame Bioferment Advanced by measuring changes in the expression of tens of thousands of genes. Roughly 2,000 genes were up-regulated and 5,000 genes down-regulated by more than the 30% limit used in this study. The results lists indicate ACB Wakame Bioferment Advanced combats the loss of strength, resiliency and function associated with aged skin.

Product Information

Product Code
20024
INCI Name
Undaria Pinnatifida Cell Culture Extract
INCI Status
Conforms
Source
Botanical
Potential Applications
Skin, Hair, Decorative Cosmetics
Suggested Use Levels
0.5 - 2.0%
Solubility
Water Soluble
Solvent
Water
Benefits
Anti-Aging, Antioxidant, Collagen Synthesis, Mitochondrial Metabolism
Preservation System
Preservative Free

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