ABS Willow Bark Extract

ABS Willow Bark Extract is standardized for 9.8 - 11.5% natural salicylates and provides formulators with the perfect alternative to synthetic salicylic acid products. This product is ideal for reducing inflammation and associated redness, plus, it acts as an efficacious antimicrobial. This water-soluble powder promotes seamless incorporation into a variety of formulas promoting all of the benefits associated with salicylic acid and none of the irritation! ABS Willow Bark Extract is perfect for creating a clear, smooth skin and a more youthful-looking aesthetic.

Efficacy Assays

  • Cellular Renewal Assay

    Increases epidermal turnover... Read More

  • Cellular Renewal Assay

    ABS Willow Bark Extract provided better cellular renewal than the 1% Synthetic Salicylic Acid. ABS Willow Bark Extract showed a 26% increase, while the synthetic showed a 22% increase. ABS Willow Bark Extract is an excellent substitute for salicylic acid in cosmetics.

  • High Resolution Skin-Imaging Assay

    Improves skin density... Read More

  • High Resolution Skin-Imaging Assay

    ABS Willow Bark Extract improved skin density by 33.59%, after 24 hours and by 44.42% after 4 weeks when compared to the untreated control. When compared to the base cream ABS Willow Bark Extract improved skin density by 36.72% after 24 hours and after 4 weeks ABS Willow Bark Extract improved density by 32.41%.

  • ORAC Assay

    Measures a material's potential to protect against oxidative stress or ROS... Read More

  • ORAC Assay

    Oxygen Radical Absorbance Capacity (ORAC) is a measure of a materials potential to protect against oxidative stress or reactive oxygen species (ROS). ABS Willow Bark Extract demonstrated significant antioxidant activity by reducing the presence of ROS compared with Trolox®, the vitamin E analog.

  • IL-6 ELISA Assay

    Measures reduction of inflammatory response... Read More

  • IL-6 ELISA Assay

    As expected, the changes in IL-6 production using ABS Willow Bark Extract appears to be dose dependent. This decrease in IL-6 production indicates a reduced inflammatory environment.

  • Anti-microbial Assay

    Organism specific-cidal activity... Read More

  • Anti-microbial Assay

    The results of the antibacterial assay indicated significant activity against all of the gram-positive bacteria tested with minimum inhibitory concentrations ranging from 0.1 to 5.0 mg/ ml. Methanolic extracts exhibited higher fungal growth inhibition, whereas the water extracts showed the least inhibition.

  • NF-kB Activation

    Inhibitis NF-κB, a potent inflammatory cellular messanger... Read More

  • NF-kB Activation

    Significant inhibition of UVB induced NK-kb activation in keratinocytes was observed when treated with 1mμ of salicylic acid for 6 hours vs. 0mμ and exposed with 0 – 25mJ/ cm2 UVB.

  • HSP 70 Protein Determination

    Heat Shock Protein 70 provides critical protection from cellular stress... Read More

  • HSP 70 Protein Determination

    Salicylic acid was found to significantly increase the induction of HSP70 Protein in keratinocytes when treated with different doses of salicylic acid (0-100mg/ml) for 24 hours.

  • DNA Repair of UVB-Induced TT-dimers

    Reduces UVB induced damage as measured by TT-dimer formation... Read More

  • DNA Repair of UVB-Induced TT-dimers

    in-vivo studies conclude that salicylic acid significantly increases DNA repair (removal rate of DNA damage) when topically pretreated with 200 mg/ml of salicylic acid (in sterile H2O) for 6 hours and then UVB irradiated at 0, 100, and 150 mJ/cm2.

Product Information

Product Code
10200
INCI Name
Salix Nigra (Willow) Bark Extract
INCI Status
Approved
Source
Botanical
Potential Applications
Skin, Hair, Decorative Cosmetics
Suggested Use Levels
2.0 - 5.0%
Solubility
Water Soluble
Solvent
N/A
Benefits
Antimicrobial, Exfoliating, Problem Skin, Anti-Aging, Antioxidant
Preservation System
Preservative Free

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