While most anti-pollution products focus on the skin surface, AC CytoPure PF addresses pollution at a cellular level. Environmental pollutants such as UV radiation and atmospheric particulates have the ability to reduce cellular glutathione levels. When the levels of glutathione are too low to keep the mitochondrial free radicals in check, the buildup of oxidative damage in the cell can change the appearance of our skin – resulting in fine lines and visible signs of aging, as well as disturbing the process of wound healing. By elevating levels of glutathione, the free radicals produced by the mitochondria can be effectively neutralized and preserve overall cell health while slowing the signs of aging. AC CytoPure PF is a new approach to anti-aging drawn from the research of sulfur biology. The product minimizes the effects of oxidative stress and accelerates wound healing, all while providing protection against cellular and external environmental pollution.
The Glutathione Assay was conducted to assess the changes in GSH concentration i... Read More
AC CytoPure PF exhibited increased concentrations of GSH in human dermal fibroblasts. This increase in GSH indicates an increase in antioxidant capacity that is known to reduce toxins and oxide species in the intracellular environment. Working to void toxins from the cell to increase overall cellular health can have a positive effect on cellular viability and attenuating the signs and symptoms of aging by regulating DNA synthesis. It can therefore be concluded that at normal use concentrations of AC CytoPure PF promotes anti-aging via GSH enhancement that in turn increases overall cell health and function.
Assesses the ability of a sample to increase cellular metabolic activity in cult... Read More
At concentrations of 0.1% and 0.01% AC CytoPure PF, nor the preservatives contained therein exhibited any inhibition of cell viability. It can therefore be concluded that at normal use concentrations AC CytoPure PF enhances cellular viability.
Improves skin density... Read More
As evidenced in a 4 week efficacy study of AC CytoPure PF on skin, skin density was improved by 22.53% after 24 hours and by 26.54% after 4 weeks when compared to the untreated control. When compared to the base cream AC CytoPure PF improved skin density by 6.34% after two weeks and after 4 weeks AC CytoPure PF improved density by 8.40%. Results indicate that AC CytoPure PF is capable of improving skin density when compared to both the untreated control as well as the base lotion.
Increase and sustained skin moisturization... Read More
In a 4 week efficacy study, AC CytoPure PF improved moisture levels by 64.2% after 24 hours and by 74.3% after 4 weeks when compared to the untreated control. Comparisons of the base lotion to the Experimental Lotion containing 2.0% AC CytoPure PF demonstrate the experimental material moisturized the skin 18.9% better after 24 hours. After four weeks the base lotion containing 2.0% AC CytoPure PF moisturized skin 12.9% better than the base lotion alone. Results indicate that AC CytoPure PF is capable of increasing moisturization when compared to both the untreated control as well as the base lotion.
Measures a material's potential to protect against oxidative stress or ROS... Read More
AC CytoPure PF exhibited antioxidant activity comparable to 200μM Trolox®. The antioxidant capacity of AC CytoPure PF increased as the concentration increased. As a result we can assure that its ability to minimize oxidative stress is dose dependent. It can therefore be concluded that AC CytoPure PF is capable of providing antioxidant properties.
Improves skin integrity and barrier function... Read More
As evidenced in a four week efficacy study of AC CytoPure PF on the skin, it can be used to effectively reduce transepidermal water loss with better results over time. When compared to the base cream AC CytoPure PF was shown to decrease transepidermal water loss by 11.15% and by 32.05% when compared to the untreated control after four weeks. Results indicate that AC CytoPure PF is capable of reducing TEWL, which allows for moisture retention.
Assesses wound healing properties of in vitro cultured human dermal fibroblasts... Read More
AC CytoPure PF was able to increase cell migration and close the scratch at a rate comparable to the positive control. The mechanisms of the cells in the in vitro scratch assay mimic the mechanisms seen in in vivo wound healing therefore we can be assured that our results are translatable outside the laboratory. With the present study we can be confident that this product has healing abilities and cell proliferation properties.
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