Phytofuse Rejuvenate ®

Phytofuse Rejuvenate ® is a natural carbohydrate scaffolding that promotes wound healing and protects the skin and hair from pollution. The isolated polysaccharides extracted from the Salvia hispanica seed have demonstrated their ability to aid in cell proliferation and impart wound healing and anti-inflammatory properties to the skin to prevent signs of aging. Phytofuse Rejuvenate ® is capable of delivering exceptional wound healing, anti-inflammatory, film forming, and anti-irritant benefits as well as improving sensorial properties of any formulation.

Efficacy Assays

  • IL-6 ELISA

    Interleukin-6 ELISA was conducted to assess the changes in IL-6 levels in Phytof... Read More

  • IL-6 ELISA

    Phytofuse Rejuvenate® exhibited anti-inflammatory effects on LPS-treated fibroblasts. This decrease in IL-6 production indicates a reduced inflammatory environment which could decrease the signs of aging and reduce the formation of fine lines and wrinkles. It can therefore be concluded that at normal use concentrations Phytofuse Rejuvenate® enhances soothing and anti-aging properties.

  • Anti-Pollution Assay

    Our pollution protection assay was conducted to assess the ability of Phytofuse ... Read More

  • Anti-Pollution Assay

    Phytofuse Rejuvenate® was able to provide pollution protection as specified by micronized carbon residue. The small amount of carbon that remains compared to the untreated control indicates the ability of Phytofuse Rejuvenate® to provide barrier protection against everyday air pollution and slow the extrinsic aging process. It can therefore be concluded that at normal use concentrations Phytofuse Rejuvenate® can be used as a skin pollution protection active ingredient.

  • Cellular Viability Assay

    Assesses the ability of a sample to increase cellular metabolic activity in cult... Read More

  • Cellular Viability Assay

    At concentrations of 1.0%, 0.1% and 0.01% Phytofuse Rejuvenate®, nor the preservatives contained therein exhibited any inhibition of cell viability. It can therefore be concluded that at normal use concentrations Phytofuse Rejuvenate® enhances cellular viability.

  • High Resolution Skin Imaging Ultrasound Assay

    Improves skin density... Read More

  • High Resolution Skin Imaging Ultrasound Assay

    As evidenced in a 4 week efficacy study of Phytofuse Rejuvenate® on skin, skin density was improved by 5.44% after 24 hours and by 28.03% after 4 weeks when compared to the untreated control. When compared to the base cream Phytofuse Rejuvenate® improved skin density by 6.29% after 24 hours and after 4 weeks Phytofuse Rejuvenate® improved density by 23.93%. Results indicate that Phytofuse Rejuvenate® is capable of improving skin density when compared to both the untreated control as well as the base lotion. Phytofuse Rejuvenate® has a positive effect on skin’s density when used at recommended use levels.

  • Moisturization Assay

    Increase and sustained skin moisturization... Read More

  • Moisturization Assay

    As evidenced in a 4 week efficacy study ofPhytofuse Rejuvenate® on skin, moisture levels were improved by 36.96% after 24 hours and by 120.89% after 4 weeks when compared to the untreated control. Comparisons of the base lotion to the Experimental Lotion containing 2.0% Phytofuse Rejuvenate® demonstrate the experimental material moisturized the skin 9.32% better after 24 hours. After four weeks the base lotion containing 2.0% Phytofuse Rejuvenate® moisturized skin 35.98% better than the base lotion alone. Results indicate that Phytofuse Rejuvenate® is capable of increasing moisturization when compared to both the untreated control as well as the base lotion.

  • ORAC Assay

    Measures a material's potential to protect against oxidative stress or ROS... Read More

  • ORAC Assay

    Phytofuse Rejuvenate® exhibited antioxidant activity comparable to 200μM Trolox®. The antioxidant capacity of Phytofuse Rejuvenate® increased as the concentration increased. As a result we can assure that its ability to minimize oxidative stress is dose dependent. It can therefore be concluded that Phytofuse Rejuvenate® is capable of providing antioxidant properties.

  • Transepidermal Water Loss

    Improves skin integrity and barrier function... Read More

  • Transepidermal Water Loss

    After one week, the solution containing 2.0% Phytofuse Rejuvenate® decreased TEWL 9.23% more effectively than the base lotion alone. After three weeks, the solution containing 2.0% Phytofuse Rejuvenate® demonstrated even more effective barrier protection, decreasing TEWL 27.14% better than the base lotion alone. Results indicate that Phytofuse Rejuvenate® is capable of reducing TEWL, which allows for moisture retention.

  • Scratch Assay

    Assesses wound healing properties of in vitro cultured human dermal fibroblasts... Read More

  • Scratch Assay

    Phytofuse Rejuvenate® was able to increase cell migration and close the scratch at a rate comparable to the positive control. The mechanisms of the cells in the in vitro scratch assay mimic the mechanisms seen in in vivo wound healing therefore we can be assured that our results are translatable outside the laboratory. With the present study we can be confident that this product has healing abilities and cell proliferation properties.

Product Information

Product Code
16882
INCI Name
Salvia Hispanica Seed Extract
INCI Status
Approved
Source
Botanical
Potential Applications
Wound Healing, Anti-Inflammatory, Film Forming, Skin Care, Hair Care, Natural Cosmetics, Antioxidant
Suggested Use Levels
1.0 - 10.0%
Solubility
Water Soluble
Solvent
Water
Benefits
Anti-Inflammatory, Wound Healing, Natural Film Former, Intense Antioxidant, Procollagen Synthesis
Preservation System
Preservative Free

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