AC Dermal Respiratory Factor Advanced PF

A global, metabolic stimulant, AC Dermal Respiratory Factor Advanced PF increases cellular oxygenation and wound healing while promoting collagen and elastin synthesis, truly increasing cellular metabolism at every level while also having the ability to reduce inflammation. Due to their efficacious soothing properties, and metabolic enhancing benefits, live yeast cell derivatives (LYCD) are widely used in the cosmetic and personal care industries. LYCD is produced when live yeast cells are exposed to stress, such as UV radiation. When added to cosmetic applications, AC Dermal Respiratory Factor Advanced PF is capable of soothing the skin and enhancing cellular function. As an added benefit, this product can also help optimize keratinization to further stimulate the health of the skin and/or scalp. Help your skin breathe easy and reap the benefits of a glowing, youthful looking aesthetic!

Efficacy Assays

  • Hyaluronic Acid Synthesis

    Measures the synthesis of hyaluronic acid by cultures of cells... Read More

  • Hyaluronic Acid Synthesis

    The results indicate that AC Dermal Respiratory Factor Advanced PF is capable of increasing the percent concentration of hyaluronic acid by approximately 42% in comparison to the control. Therefore, we can assume that AC Dermal Respiratory Factor Advanced PF may be useful for retaining epidermal moisture.

  • ORAC Assay

    Measures a material's potential to protect against oxidative stress or ROS... Read More

  • ORAC Assay

    AC Dermal Respiratory Factor Advanced PF exhibited antioxidant activity comparable to Trolox®. The antioxidant capacity of AC Dermal Respiratory Factor Advanced PF increased as the concentration increased, allowing us to deduce that its ability to minimize oxidative stress is dose dependent.

  • Procollagen Assay

    Stimulates procollagen production in situ... Read More

  • Procollagen Assay

    The ELISA indicates that AC Dermal Respiratory Factor Advanced PF is capable of increasing the expression of procollagen type 1-C peptide in the fibroblast cell culture model. AC Dermal Respiratory Factor was shown to be comparable to Magnesium Ascorbyl Phosphate in increasing the synthesis of Collagen Type I. These findings suggest that AC Dermal Respiratory Factor Advanced PF would be useful in cosmetic preparations to stimulate collagen type I production in-situ.

  • Reduction of Sunburn Pain

    Evaluates the ability of a test material to reduce pain resulting from over expo... Read More

  • Reduction of Sunburn Pain

    Topical application of AC Dermal Respiratory Factor Advanced PF is capable of producing consumer perceivable reductions in erythema and discomfort resulting from overexposure to light. It was also noted among those panelists complying with the one-week application period that there was a marked reduction in skin peeling to areas where lotion containing AC Dermal Respiratory Factor Advanced PF was applied.

  • Cellular Viability Assay

    Assesses the ability of a sample to increase cellular metabolic activity in cult... Read More

  • Cellular Viability Assay

    AC Dermal Respiratory Factor Advanced PF exhibited positive results by increasing cell metabolism. The increase in fluorescent signal indicates an increase in cellular metabolism and viability post AC Dermal Respiratory Factor Advanced PF treatment. For these reasons, we can assume AC Dermal Respiratory Factor Advanced PF is suitable for cosmetic applications designed to increase cell viability and metabolism.

  • High Resolution Skin Imaging Ultrasound Assay

    Improves skin density... Read More

  • High Resolution Skin Imaging Ultrasound Assay

    As evidenced in a 4 week efficacy study of AC Dermal Respiratory Factor Advanced PF on skin, skin density was improved by 9.50% after one week and by 17.39% after 4 weeks when compared to the untreated control. When compared to the base cream AC Dermal Respiratory Factor Advanced PF improved skin density for the first two weeks of the trial, working 9.54% better than the base lotion after two weeks. Although still working better than the base lotion at the end of 4 weeks, AC Dermal Respiratory Factor Advanced PF improved density only 2.24% better than the base lotion. Results indicate that AC Dermal Respiratory Factor Advanced PF is capable of improving skin density when compared to both the untreated control as well as the base lotion. AC Dermal Respiratory Factor Advanced PF has a strong positive effect on skin’s density when used at recommended use levels.

  • Moisturization Assay

    Increase and sustained skin moisturization... Read More

  • Moisturization Assay

    As evidenced in a 4 week efficacy study of AC Dermal Respiratory Factor Advanced PF on skin, moisture levels were improved by 44.60% after 24 hours and by 95.0% after 4 weeks when compared to the untreated control. When compared to the base cream AC DRF Advanced PF improved moisturization by 12.14% and after 4 weeks AC DRF Advanced PF improved moisturization by 33.74%. Results indicate that AC Dermal Respiratory Factor Advaced PF is capable of increasing moisturization when compared to both the untreated control as well as the base lotion. The present study confirms that AC Dermal Respiratory Factor Advanced PF is not only capable of providing functional benefits but it is also capable of providing moisturizing and skin hydrating benefits when added to cosmetic applications.

  • Pigmentation Assay

    Reduces erythema and melanin levels... Read More

  • Pigmentation Assay

    As evidenced in a 4 week efficacy study of AC Dermal Respiratory Factor Advanced PF on skin, erythema values were decreased 4.73% more than the untreated test after one week. After 4 weeks, erythema values were decreased by 15.16% more than the untreated site. When compared to the base cream AC Dermal Respiratory Factor Advanced PF decreased pigmentation 1.73% more effectively after week one and after 4 weeks AC Dermal Respiratory Factor decreased pigmentation 13.11% more effectively than the base lotion alone. Results indicate that AC Dermal Respiratory Factor Advanced PF is capable of decreasing erythema when compared to both the untreated control as well as the base lotion. AC Dermal Respiratory Factor Advanced PF has a lightening effect on skin’s pigmentation when used at recommended use levels.

  • Scratch Assay

    Assesses wound healing properties of in vitro cultured human dermal fibroblasts... Read More

  • Scratch Assay

    AC Dermal Respiratory Factor Advanced PF was able to increase cell migration and close the scratch at a rate comparable to the positive control. The mechanisms of the cells in the in vitro scratch assay mimic the mechanisms seen in in vivo wound healing therefore we can be assured that our results are translatable outside the laboratory. AC Dermal Respiratory Factor Advanced PF was designed to increase cellular respiration, metabolism, and collagen synthesis. With the present study we can also be confident that this product has healing abilities and cell proliferation properties.

  • Transepidermal Water Loss

    Improves skin integrity and barrier function... Read More

  • Transepidermal Water Loss

    As evidenced in a four week efficacy study of AC Dermal Respiratory Factor Advanced PF on the skin, it can be used to effectively reduce transepidermal water loss with better results over time. When compared to the base cream AC Dermal Respiratory Factor Advanced PF was shown to decrease transepidermal water loss by 29.24% and by 50.00% when compared to the untreated control after four weeks. Results indicate that AC Dermal Respiratory Factor Advanced PF is capable of reducing TEWL, which allows for moisture retention. AC Dermal Respiratory Factor Advanced PF was designed to provide moisture retention benefits, however with the present study we can confirm that this unique ingredient is not only capable of providing functional benefits but it is also capable of providing a decrease in transepidermal water loss therefore promoting moisture retention benefits when added to cosmetic applications.

Product Information

Product Code
20219PF
INCI Name
Water & Saccharomyces Lysate Extract
INCI Status
Conforms
Source
Yeast
Potential Applications
Skin, Hair, Decorative Cosmetics
Suggested Use Levels
0.50 - 1.00%
Solubility
Water Soluble
Solvent
Water
Benefits
Cellular Respiration, Cellular Metabolism, Collagen Synthesis, Elastin Synthesis, Soothing, Wound Healing
Preservation System
Preservative Free

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